ABSTRACT
Objective@#To observe the ocular surface function changes of dry eye patients with seborrheic dermatitis and discuss the significance of seborrheic dermatitis in ocular surface damage.@*Methods@#A cohort study was performed.Forty-nine patients (49 eyes) who were initial diagnosed with dry eye enrolled in General Hospital of Tianjin Medical University from October 2015 to March 2016 were divided into 2 groups, including 21 patients with seborrheic dermatitis and 28 patients without seborrheic dermatitis.Gender, age, meibomian gland dysfunction (MGD), eyelid margin scores, eyelid secretions scores, meibomian gland imaging scores, conjunctival congestion scores, ocular surface disease index (OSDI), Schirmer Ⅰtest (SⅠt), break-up time of tear film (BUT), fluorescent integral score were examined and compared.The study was followed the Declaration of Helsinki and was approved by General Hospital of Tianjin Medical University (No.IRB2015-YX-069). Written informed consent was obtained from all subjects before entering the study.@*Results@#There were not significant differences in gender and ages (χ2=1.536, P=0.215; t=0.642, P=0.524). The rate of MGD in seborrheic dermatitis group was 57.15%, which was significantly higher than that in the non-seborheic dermatitis group (25.00%), with significan difference between the two groups (χ2=5.222, P=0.022). There were significant differences in eyelid margin scores, eyelid secretions scores, meibomian gland imaging scores, fluorescent integral scores between the two groups (Z=2.105, 3.303, 3.368, 3.036, all at P<0.05). The OSDI in the seborheic dermatitis group was 26.43±8.05, which was significantly larger than that in the non-seborheic dermatitis group (16.75±5.74); the BUT in the seborheic dermatitis group was (6.14±1.98)s, which was significantly shorter than that in the non-seborheic (8.75±1.38)s (t=4.918, 5.434; both at P<0.05).@*Conclusions@#Seborrheic dermatitis may aggravate ocular surface dysfunction in dry eye patients.
ABSTRACT
Objective To observe the ocular surface function changes of dry eye patients with seborrheic dermatitis and discuss the significance of seborrheic dermatitis in ocular surface damage. Methods A cohort study was performed. Forty-nine patients (49 eyes) who were initial diagnosed with dry eye enrolled in General Hospital of Tianjin Medical University from October 2015 to March 2016 were divided into 2 groups,including 21 patients with seborrheic dermatitis and 28 patients without seborrheic dermatitis. Gender, age, meibomian gland dysfunction (MGD), eyelid margin scores, eyelid secretions scores, meibomian gland imaging scores, conjunctival congestion scores,ocular surface disease index ( OSDI) ,Schirmer Ⅰtest ( SⅠt) ,break-up time of tear film ( BUT) ,fluorescent integral score were examined and compared. The study was followed the Declaration of Helsinki and was approved by General Hospital of Tianjin Medical University (No. IRB2015-YX-069). Written informed consent was obtained from all subjects before entering the study. Results There were not significant differences in gender and ages (χ2=1. 536,P=0. 215;t=0. 642,P=0. 524). The rate of MGD in seborrheic dermatitis group was 57. 15％,which was significantly higher than that in the non-seborheic dermatitis group (25. 00％),with significan difference between the two groups (χ2 =5. 222,P=0. 022). There were significant differences in eyelid margin scores,eyelid secretions scores,meibomian gland imaging scores,fluorescent integral scores between the two groups (Z=2. 105,3. 303,3. 368, 3. 036,all at P<0. 05). The OSDI in the seborheic dermatitis group was 26. 43±8. 05,which was significantly larger than that in the non-seborheic dermatitis group (16. 75±5. 74);the BUT in the seborheic dermatitis group was (6. 14± 1. 98)s,which was significantly shorter than that in the non-seborheic (8. 75±1. 38)s (t=4. 918,5. 434;both at P<0. 05). Conclusions Seborrheic dermatitis may aggravate ocular surface dysfunction in dry eye patients.
ABSTRACT
Objective To evaluate the successful rate of surgical treatment of retinal detachment due to macular hole in high myopia, and to analyze the relative reasons. Methods Eleven eyes of 11 high myopic patients with retinal detachment due to macular hole underwent vitrectomy combined with the adjunct of 18%C 3F 8 or silicone oil. Strict prone position was conducted at least 2 weeks postoperatively. Results Macular hole closed and retina reattached in 10 eyes. Visual acuity was increased in 10 eyes, and no change in 1 eye. Postoperative complications mainly included nuclear sclerosis of the lens(1 eye), intraocular pressure elevation (1 eye), fibrosis exudates (2 eyes),and diplopia (1 eye). Conclusion The use of vitrectomy combined with the adjunct of 18%C3F8 or silicone oil is a safe and effective method in treating retinal detachment due to macular hole in high myopia. Preoperative careful examination of ocular fundus, rational surgical design, and better surgical expertise are basic factors in treating this disease.